Johannes Wirth
Bachelor and Master studies in Chemical Biology at University Konstanz. PhD at Helmholtz Center Munich on the development of a novel spatial transcriptomics technology. Now postdoctoral researcher at the Institute of Pathology of the Technical University Munich combining in situ sequencing, pathology and computational analysis to dissect the intra-tumoral heterogeneity of different cancer entities.
Sessions
Intra-tumoral heterogeneity contributes to low survival rates in pancreatic ductal adenocarcinoma (PDAC). Using in situ sequencing and an interdisciplinary analysis approach, we will map tumor subtypes, immune cells, and fibroblasts in a large cohort of PDAC patients to study cellular processes in primary tumors and metastases and decipher the impact of tumor architecture on treatment response.